GBP3

Across TCGA cell cohorts, GBP3 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible GBP3-associated genes across cancer lineages are IL1F10, FEZF2, and LAIR2. Each is linked with GBP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GBP3-to-partner and partner-to-GBP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IL1F10 grouped by GBP3-low versus GBP3-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GBP3→partner) and Y-score (partner→GBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	IL1F10 →	+0.211	+4.369	<.001	.008	3	1
SOFT_TISSUE	FEZF2 →	+0.172	+4.222	<.001	.007	3	1
SOFT_TISSUE	LAIR2 →	+0.951	+4.417	<.001	.004	3	1
SOFT_TISSUE	CCDC197 →	+0.124	+4.222	<.001	.007	3	1
SOFT_TISSUE	POTEB →	+0.053	+4.369	<.001	.008	3	1
LARGE_INTESTINE	LILRA5 →	+0.015	+3.562	.003	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

IL1F10 by GBP3 expression — SOFT_TISSUE

Explore this box plot interactively →