GAU1

Across TCGA pan-cancer cohorts, GAU1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of GAU1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where GAU1 RNA is repressed in tumor relative to normal tissue. In most cancer types GAU1 is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

LUAD, LUSC, and THCA are the cancer types where GAU1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GAU1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	II,III,IV	−0.223	<.001	7	view →
LUSC	Female	II,III,IV	−0.232	<.001	6	view →
THCA	Female	All	−0.087	<.001	6	view →
BLCA	Male	IV	−0.285	.036	1	view →
CHOL	Male	All	+0.223	.001	1	view →
KICH	All	III,IV	−0.074	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

GAU1–LUAD

Open the LUAD breakdown →