GATD3B

Across TCGA patient cohorts, GATD3B RNA expression is significantly associated with the go_rna of many other GO terms, with 6,417 significant associations in total. LGG shows the largest number of these associations.

The most reproducible GATD3B-associated GO terms across cancer lineages are Protein insertion into ER membrane by stop-transfer membrane-anchor sequence, tRNA thio-modification, and Tail-anchored membrane protein insertion into ER membrane. Each is linked with GATD3B in more than 20 cancer types. Because this analysis shows association rather than direction, both GATD3B-to-partner and partner-to-GATD3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein insertion into ER membrane by stop-transfer membrane-anchor sequence grouped by GATD3B-low versus GATD3B-high in ACC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GATD3B→partner) and Y-score (partner→GATD3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	Protein insertion into ER membrane by stop-transfer membrane-anchor sequence →	+0.058	+0.851	<.001	<.001	2	21
READ	tRNA thio-modification →	+0.062	+0.677	<.001	<.001	3	19
ACC	Tail-anchored membrane protein insertion into ER membrane →	+0.038	+0.609	<.001	<.001	3	16
ACC	Peroxisomal transport →	+0.049	+0.851	<.001	<.001	3	15
UVM	Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.058	+1.037	<.001	<.001	3	15
UVM	Ribosomal small subunit assembly →	+0.038	+0.673	.002	.003	2	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,417 associations by consensus.

Protein insertion into ER membrane by stop-transfer membrane-anchor sequence by GATD3B expression — ACC

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