GATD3B

Across TCGA pan-cancer cohorts, GATD3B RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated GATD3B data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher GATD3B RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated GATD3B expression acts as an unfavorable survival marker, although some lineages such as STAD and KIRP show a favorable association.

UVM, STAD, and CESC are the cancer types where GATD3B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Quartile	All	0.465	0.875	<.001	62	view →
STAD	DFS	Quartile	III,IV	0.550	0.203	.005	56	view →
CESC	DFS	Median	All	0.670	0.798	.011	24	view →
LGG	DFS	Median	All	0.800	0.864	.002	15	view →
COAD	DFS	Median	IV	0.226	0.687	.001	14	view →
KIRP	OS	Tertile	All	0.870	0.565	.041	13	view →
PRAD	DFS	Quartile	All	0.627	0.890	.004	12	view →
HNSC	DFS	Tertile	III,IV	0.483	0.311	.007	12	view →
OV	OS	Median	III,IV	0.266	0.361	.008	12	view →
CHOL	OS	Tertile	II,III,IV	0.752	0.267	.015	8	view →
SKCM	OS	Tertile	III,IV	0.868	0.758	.011	8	view →
LUAD	DFS	Tertile	All	0.634	0.725	.022	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

GATD3B–UVM (DFS)

Open the UVM breakdown →