GATD3A

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GATD3A mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GATD3A-associated genes across cancer lineages are FTMT, C6orf118, and ACSM6. Each is linked with GATD3A in more than 1 cancer types. Because this analysis shows association rather than direction, both GATD3A-to-partner and partner-to-GATD3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FTMT grouped by GATD3A-low versus GATD3A-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GATD3A→partner) and Y-score (partner→GATD3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUEFTMT →+0.086+5.977<.001.00131
LARGE_INTESTINEC6orf118 →+0.175+3.793<.001.00731
LARGE_INTESTINEACSM6 →+0.027+4.169<.001.00731
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

FTMT by GATD3A expression — SOFT_TISSUE

Box plot of FTMT in GATD3A-low vs GATD3A-high samples in SOFT_TISSUE.

Explore this box plot interactively →

Exploration