GATC

Across TCGA pan-cancer cohorts, GATC Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated GATC data layer compared with 24 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher GATC Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated GATC expression acts as an unfavorable survival marker.

LIHC, SKCM, and LUSC are the cancer types where GATC Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	All	0.198	0.777	.006	18	view →
SKCM	DFS	Median	All	0.012	0.738	<.001	18	view →
LUSC	OS	Median	All	0.170	0.675	.025	15	view →
BLCA	OS	Median	All	0.228	0.720	.010	9	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

GATC–LIHC (OS)

Open the LIHC breakdown →