GATB

Across TCGA cell cohorts, GATB RNA expression is significantly associated with the go_rna of many other GO terms, with 2,888 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GATB-associated GO terms across cancer lineages are Amino acid activation, tRNA aminoacylation, and U1 snRNA 3'-end processing. Each is linked with GATB in more than 12 cancer types. Because this analysis shows association rather than direction, both GATB-to-partner and partner-to-GATB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Amino acid activation grouped by GATB-low versus GATB-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GATB→partner) and Y-score (partner→GATB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Amino acid activation →	+0.084	+0.822	<.001	.001	3	13
KIDNEY	tRNA aminoacylation →	+0.084	+0.822	<.001	.001	3	13
LARGE_INTESTINE	U1 snRNA 3'-end processing →	+0.104	+0.705	<.001	<.001	3	11
LARGE_INTESTINE	U5 snRNA 3'-end processing →	+0.104	+0.705	<.001	<.001	3	11
BLOOD_Lymphoma	Mitochondrial ribosome assembly →	+0.080	+0.636	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Glutaminyl-tRNAGln biosynthesis via transamidation →	+0.094	+0.729	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,888 associations by consensus.

Amino acid activation by GATB expression — KIDNEY

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