GATAD2A

Across TCGA patient cohorts, GATAD2A mutation is significantly associated with the total protein of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GATAD2A-associated genes across cancer lineages are Caspase-7-cleavedD198, Gab2, and ASNS. Each is linked with GATAD2A in more than 1 cancer types. Because this analysis shows association rather than direction, both GATAD2A-to-partner and partner-to-GATAD2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by GATAD2A-low versus GATAD2A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GATAD2A→partner) and Y-score (partner→GATAD2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.453	+1.341	.022	.043	3	2
STAD	Gab2 →	-0.499	-3.169	.012	.019	3	1
STAD	ASNS →	+0.544	+3.169	.012	.019	3	1
UCEC	EGFR_pY1173 →	+0.062	+1.348	.021	.018	3	1
UCEC	A-Raf_pS299 →	-0.102	-2.222	.011	.010	3	1
UCEC	GSK-3_pS9 →	-0.317	-2.115	.019	.016	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

Caspase-7-cleavedD198 by GATAD2A expression — UCEC

Explore this box plot interactively →