GATAD2A

Across TCGA pan-cancer cohorts, GATAD2A RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of GATAD2A’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where GATAD2A RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GATAD2A is over-expressed in tumor.

HNSC, BLCA, and KIRC are the cancer types where GATAD2A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GATAD2A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	+1.088	<.001	12	view →
BLCA	Male	III,IV	+1.328	<.001	11	view →
KIRC	Female	All	+0.596	<.001	11	view →
COAD	All	III,IV	+0.593	<.001	11	view →
LIHC	Female	II,III,IV	+0.998	<.001	9	view →
STAD	Male	II,III,IV	+1.297	<.001	8	view →
THCA	Male	All	+0.378	<.001	8	view →
KIRP	All	II,III,IV	+0.478	.001	7	view →
UCEC	All	III,IV	+1.120	<.001	6	view →
LUSC	Male	II,III,IV	+0.754	<.001	6	view →
BRCA	All	II,III,IV	+0.484	<.001	6	view →
CHOL	Male	All	+2.045	<.001	5	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

GATAD2A–HNSC

Open the HNSC breakdown →