GATAD2A

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GATAD2A mutation is significantly associated with the RNA expression of many other genes, with 38 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GATAD2A-associated genes across cancer lineages are TLE7, OR8B12, and TMEM95. Each is linked with GATAD2A in more than 1 cancer types. Because this analysis shows association rather than direction, both GATAD2A-to-partner and partner-to-GATAD2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TLE7 grouped by GATAD2A-low versus GATAD2A-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GATAD2A→partner) and Y-score (partner→GATAD2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaTLE7 →+0.025+4.384<.001.00632
SOFT_TISSUEOR8B12 →+0.066+5.369<.001.00431
SOFT_TISSUETMEM95 →+0.027+4.930.001.00831
SOFT_TISSUEOR8B8 →+0.039+5.369<.001.00431
SOFT_TISSUEOR10D3 →+0.081+4.930<.001.00831
SOFT_TISSUEOR8B3 →+0.032+4.930<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

TLE7 by GATAD2A expression — BLOOD_Leukemia

Box plot of TLE7 in GATAD2A-low vs GATAD2A-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration