GATA5

Across TCGA patient cohorts, GATA5 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GATA5-associated genes across cancer lineages are p62 Lck ligand and PDK1_pS241. Each is linked with GATA5 in more than 1 cancer types. Because this analysis shows association rather than direction, both GATA5-to-partner and partner-to-GATA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p62 Lck ligand grouped by GATA5-low versus GATA5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GATA5→partner) and Y-score (partner→GATA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p62 Lck ligand →	+0.301	+3.009	.047	.019	3	1
UCEC	PDK1_pS241 →	+0.186	+1.887	.019	.031	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

p62 Lck ligand by GATA5 expression — UCEC

Explore this box plot interactively →