GATA5

Across TCGA cell cohorts, GATA5 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,607 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GATA5-associated GO terms across cancer lineages are Regulation of postsynaptic membrane potential, Aerobic electron transport chain, and Cytoplasmic translation. Each is linked with GATA5 in more than 6 cancer types. Because this analysis shows association rather than direction, both GATA5-to-partner and partner-to-GATA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of postsynaptic membrane potential grouped by GATA5-low versus GATA5-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GATA5→partner) and Y-score (partner→GATA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Regulation of postsynaptic membrane potential →	-0.079	-0.428	<.001	.001	3	7
BREAST	Aerobic electron transport chain →	+0.087	+1.104	<.001	<.001	3	5
BLOOD_Leukemia	Cytoplasmic translation →	+0.055	+0.635	<.001	.002	2	6
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.109	+0.643	.001	.007	3	5
BREAST	Adenylate cyclase-activating G protein-coupled bile acid receptor signaling pathway →	+0.065	+1.139	.002	<.001	3	5
BREAST	ATP synthesis coupled electron transport →	+0.103	+1.367	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,607 associations by consensus.

Regulation of postsynaptic membrane potential by GATA5 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →