GATA3

Across TCGA patient cohorts, GATA3 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,982 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GATA3-associated proteins across cancer lineages are PREX1, RAC2, and ANKRD44. Each is linked with GATA3 in more than 6 cancer types. Because this analysis shows association rather than direction, both GATA3-to-partner and partner-to-GATA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GATA3 versus PREX1 in BRCA, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GATA3→partner) and Y-score (partner→GATA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PREX1 →	+0.747	+2.576	<.001	<.001	3	7
CCRCC	RAC2 →	+0.748	+0.570	<.001	<.001	3	7
OV	ANKRD44 →	+0.416	+0.695	.006	.008	3	7
COAD	LCP2 →	+0.470	+0.420	<.001	.001	3	7
UCEC	PLEKHO2 →	+0.380	+0.679	.002	.003	3	7
BRCA	EVL_S246 →	+1.291	+2.486	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,982 associations by consensus.

GATA3 vs PREX1 — BRCA

Explore this scatter interactively →