GATA3

Across TCGA patient cohorts, GATA3 protein abundance is significantly associated with the RNA expression of many other genes, with 8,783 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GATA3-associated genes across cancer lineages are TNFSF13B, IL7, and SLAMF1. Each is linked with GATA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GATA3-to-partner and partner-to-GATA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GATA3 versus TNFSF13B in CCRCC, with a Pearson correlation of -0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GATA3→partner) and Y-score (partner→GATA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	TNFSF13B →	-0.821	-0.442	.001	.004	3	2
CCRCC	IL7 →	-0.552	-0.497	<.001	<.001	3	2
CCRCC	SLAMF1 →	-1.034	-0.660	<.001	.001	3	2
BRCA	ADGRE5 →	-0.712	-0.738	<.001	<.001	3	2
BRCA	KCNK1 →	-1.193	-0.673	.002	<.001	3	2
CCRCC	MARCHF9 →	+0.538	+0.452	.005	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,783 associations by consensus.

GATA3 vs TNFSF13B — CCRCC

Explore this scatter interactively →