GATA3

Across TCGA cell cohorts, GATA3 RNA expression is significantly associated with the RNA expression of many other genes, with 11,924 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GATA3-associated genes across cancer lineages are NTN4, AAK1, and LY6E. Each is linked with GATA3 in more than 7 cancer types. Because this analysis shows association rather than direction, both GATA3-to-partner and partner-to-GATA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GATA3 versus NTN4 in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.61.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GATA3→partner) and Y-score (partner→GATA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	NTN4 →	+2.703	+1.717	<.001	<.001	3	8
BLOOD_Lymphoma	AAK1 →	+1.791	+2.319	<.001	<.001	3	6
BLOOD_Lymphoma	LY6E →	+3.242	+1.944	<.001	<.001	3	6
URINARY_TRACT	MB →	+3.468	+2.978	<.001	<.001	3	6
LIVER	LYPD6B →	+2.604	+1.744	<.001	<.001	3	6
BLOOD_Leukemia	IKZF2 →	+2.237	+2.138	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,924 associations by consensus.

GATA3 vs NTN4 — UPPER_AERODIGESTIVE_TRACT

Explore this scatter interactively →