Across TCGA patient cohorts, GAST RNA expression is significantly associated with the protein abundance of many other proteins, with 10,931 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GAST-associated proteins across cancer lineages are FRMD6_S544, SMAP2_S235, and SOWAHC. Each is linked with GAST in more than 3 cancer types. Because this analysis shows association rather than direction, both GAST-to-partner and partner-to-GAST results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GAST→partner) and Y-score (partner→GAST) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FRMD6_S544 →	+0.850	+1.461	<.001	<.001	3	4
LSCC	SMAP2_S235 →	-0.401	-1.368	<.001	<.001	3	3
HNSC	SOWAHC →	+0.471	+1.503	<.001	<.001	3	3
HNSC	TACC2_S2512 →	+0.595	+1.040	<.001	.002	3	3
HNSC	BAIAP2 →	+0.681	+1.501	<.001	<.001	3	3
BRCA	CORO1C →	+0.342	+0.137	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,931 associations by consensus.

Exploration

GAST survival (RNA) · tumor vs normal (RNA) · all GAST data types