Across TCGA patient cohorts, GAST mutation is significantly associated with the RNA expression of many other genes, with 46 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible GAST-associated genes across cancer lineages are MIR7155, OR4K15, and MIR6747. Each is linked with GAST in more than 1 cancer types. Because this analysis shows association rather than direction, both GAST-to-partner and partner-to-GAST results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAST→partner) and Y-score (partner→GAST) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR7155 →	+1.015	+5.279	<.001	<.001	3	2
UCEC	OR4K15 →	+0.120	+4.352	<.001	.008	3	1
SKCM	MIR6747 →	+0.663	+3.894	.001	.008	3	1
SKCM	TUBAP1 →	+0.053	+4.156	.008	.004	3	1
SKCM	OR9A3P →	+0.107	+3.952	.005	.007	3	1
SKCM	RN7SL862P →	+0.242	+3.765	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

Exploration

GAST survival (RNA) · tumor vs normal (RNA) · all GAST data types