GASK1B

Across TCGA cell cohorts, GASK1B mutation is significantly associated with the RNA expression of many other genes, with 42 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GASK1B-associated genes across cancer lineages are OR4E2, C12orf65, and TKTL2. Each is linked with GASK1B in more than 1 cancer types. Because this analysis shows association rather than direction, both GASK1B-to-partner and partner-to-GASK1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4E2 grouped by GASK1B-low versus GASK1B-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GASK1B→partner) and Y-score (partner→GASK1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR4E2 →	+0.003	+4.247	<.001	.004	3	2
LARGE_INTESTINE	C12orf65 →	+0.643	+3.082	<.001	.007	3	1
LARGE_INTESTINE	TKTL2 →	+0.038	+3.509	<.001	.001	3	1
LARGE_INTESTINE	SBSPON →	+1.938	+3.302	<.001	.008	3	1
LARGE_INTESTINE	KLF13 →	+0.981	+3.064	.001	.009	3	1
LARGE_INTESTINE	OR10W1 →	+0.008	+2.977	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

OR4E2 by GASK1B expression — BLOOD_Lymphoma

Explore this box plot interactively →