GAS7

Across TCGA patient cohorts, GAS7 mutation is significantly associated with the RNA expression of many other genes, with 2,949 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GAS7-associated genes across cancer lineages are E2F6P1, RN7SKP135, and RNA5SP73. Each is linked with GAS7 in more than 3 cancer types. Because this analysis shows association rather than direction, both GAS7-to-partner and partner-to-GAS7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, E2F6P1 grouped by GAS7-low versus GAS7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAS7→partner) and Y-score (partner→GAS7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	E2F6P1 →	+0.012	+2.742	<.001	.008	3	4
UCEC	RN7SKP135 →	+0.024	+3.936	<.001	.004	3	3
PAAD	RNA5SP73 →	+0.403	+5.392	<.001	.005	3	2
COAD	SPTLC1P5 →	+0.327	+3.661	<.001	.002	3	2
LUAD	IGKV2D-10 →	+0.261	+2.721	.003	.006	3	2
LUAD	LINC00564 →	+0.169	+3.592	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,949 associations by consensus.

E2F6P1 by GAS7 expression — UCEC

Explore this box plot interactively →