GAS6-DT

Across TCGA pan-cancer cohorts, GAS6-DT RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated GAS6-DT data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher GAS6-DT RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated GAS6-DT expression acts as an unfavorable survival marker, although some lineages such as KIRC and THCA show a favorable association.

BLCA, MESO, and KIRC are the cancer types where GAS6-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Quartile	All	0.271	0.721	<.001	105	view →
MESO	OS	Median	All	0.418	0.675	<.001	98	view →
KIRC	OS	Median	All	0.856	0.754	<.001	66	view →
KIRP	DFS	Tertile	All	0.355	0.711	.002	42	view →
COAD	OS	Median	III,IV	0.526	0.840	.001	38	view →
UVM	OS	Tertile	All	0.435	0.733	.007	37	view →
READ	OS	Median	III,IV	0.433	1.000	.002	29	view →
THCA	DFS	Median	II,III,IV	0.963	0.879	.009	20	view →
OV	OS	Median	IV	0.638	0.837	.009	18	view →
LGG	OS	Median	All	0.840	0.930	.001	15	view →
PAAD	DFS	Tertile	All	0.197	0.364	.018	11	view →
HNSC	OS	Median	All	0.628	0.781	.003	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

GAS6-DT–BLCA (DFS)

Open the BLCA breakdown →