GAS6-AS1

Across TCGA pan-cancer cohorts, GAS6-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated GAS6-AS1 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher GAS6-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated GAS6-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRP and UCEC show a favorable association.

KIRP, UVM, and UCEC are the cancer types where GAS6-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Tertile	II,III,IV	0.961	0.398	<.001	138	view →
UVM	DFS	Median	All	0.427	0.760	<.001	123	view →
UCEC	DFS	Median	All	0.891	0.789	<.001	82	view →
LIHC	DFS	Quartile	III,IV	0.424	0.058	.001	68	view →
LUAD	OS	Median	All	0.441	0.283	<.001	63	view →
LGG	DFS	Median	All	0.623	0.836	<.001	52	view →
ACC	OS	Tertile	All	0.873	0.351	.002	37	view →
ESCA	OS	Quartile	III,IV	0.739	0.400	.003	35	view →
OV	OS	Quartile	IV	0.325	0.641	.003	30	view →
LUSC	DFS	Quartile	II,III,IV	0.234	0.568	.001	26	view →
SKCM	OS	Median	III,IV	0.504	0.309	.008	16	view →
PRAD	DFS	Median	All	0.676	0.888	<.001	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

GAS6-AS1–KIRP (OS)

Open the KIRP breakdown →