GARNL3

Across TCGA patient cohorts, GARNL3 mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GARNL3-associated genes across cancer lineages are GATA3, VHL, and Caspase-7-cleavedD198. Each is linked with GARNL3 in more than 2 cancer types. Because this analysis shows association rather than direction, both GARNL3-to-partner and partner-to-GARNL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GATA3 grouped by GARNL3-low versus GARNL3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GARNL3→partner) and Y-score (partner→GARNL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	GATA3 →	+0.202	+2.178	.035	.035	3	3
UCEC	VHL →	-0.697	-1.925	<.001	.004	3	3
UCEC	Caspase-7-cleavedD198 →	+0.483	+1.604	.008	.010	3	3
COAD	Rad50 →	-0.299	-2.974	.008	.035	3	2
COAD	E-Cadherin →	-0.810	-3.313	.006	.010	3	2
UCEC	A-Raf_pS299 →	-0.106	-1.847	.004	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

GATA3 by GARNL3 expression — COAD

Explore this box plot interactively →