GARNL3

Across TCGA cell cohorts, GARNL3 mutation is significantly associated with the RNA expression of many other genes, with 484 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GARNL3-associated genes across cancer lineages are GHRHR, OR2F2, and DDHD1. Each is linked with GARNL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GARNL3-to-partner and partner-to-GARNL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GHRHR grouped by GARNL3-low versus GARNL3-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GARNL3→partner) and Y-score (partner→GARNL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	GHRHR →	+0.069	+5.087	<.001	.004	3	1
KIDNEY	OR2F2 →	+0.020	+5.000	<.001	.005	3	1
LARGE_INTESTINE	DDHD1 →	+0.870	+3.364	<.001	.002	3	1
LARGE_INTESTINE	TMED8 →	+0.628	+3.364	.001	.002	3	1
LARGE_INTESTINE	CCM2L →	+0.392	+3.125	<.001	.008	3	1
LARGE_INTESTINE	NISCH →	+0.730	+3.067	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 484 associations by consensus.

GHRHR by GARNL3 expression — URINARY_TRACT

Explore this box plot interactively →