GAPT

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GAPT protein abundance is significantly associated with the RNA expression of many other genes, with 401 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GAPT-associated genes across cancer lineages are SLC8A3, HM13, and AHCY. Each is linked with GAPT in more than 1 cancer types. Because this analysis shows association rather than direction, both GAPT-to-partner and partner-to-GAPT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GAPT versus SLC8A3 in GBM, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAPT→partner) and Y-score (partner→GAPT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMSLC8A3 →+1.405+0.727.004.00131
GBMHM13 →-0.463-0.573.008.00231
GBMAHCY →-0.456-0.689<.001<.00131
GBMTNFSF13B →+0.779+0.556.002.00231
GBMSGK3 →+0.491+0.491.008.00931
GBMPPP1R37 →-0.439-0.571<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 401 associations by consensus.

GAPT vs SLC8A3 — GBM

Per-sample scatter of GAPT vs SLC8A3 in GBM (Pearson r = 0.49).

Explore this scatter interactively →

Exploration