GAPDHP70

Across TCGA pan-cancer cohorts, GAPDHP70 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of GAPDHP70’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where GAPDHP70 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GAPDHP70 is over-expressed in tumor.

KIRC, COAD, and HNSC are the cancer types where GAPDHP70 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GAPDHP70 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	III,IV	+0.557	<.001	12	view →
COAD	Female	All	+1.097	<.001	9	view →
HNSC	All	II,III,IV	+0.152	.005	7	view →
UCEC	All	All	+0.654	.001	6	view →
LUSC	All	All	+0.270	<.001	6	view →
KIRP	Male	III,IV	+0.269	.001	6	view →
LUAD	All	All	+0.252	<.001	5	view →
LIHC	All	All	+0.070	<.001	5	view →
BRCA	Female	II,III,IV	+0.095	.005	4	view →
THCA	All	All	+0.082	.002	4	view →
PRAD	All	All	+0.081	.012	2	view →
READ	All	II,III,IV	+0.547	.026	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

GAPDHP70–KIRC

Open the KIRC breakdown →