Across TCGA pan-cancer cohorts, GAPDHP55 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of GAPDHP55’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where GAPDHP55 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GAPDHP55 is over-expressed in tumor.
KIRC, LUSC, and HNSC are the cancer types where GAPDHP55 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GAPDHP55 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.