GAPDHP34

Across TCGA pan-cancer cohorts, GAPDHP34 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of GAPDHP34’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where GAPDHP34 RNA is repressed in tumor relative to normal tissue. In most cancer types GAPDHP34 is over-expressed in tumor, although a few such as THCA and ESCA show the opposite, repressed pattern.

THCA, KIRP, and ESCA are the cancer types where GAPDHP34 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GAPDHP34 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.039	<.001	2	view →
KIRP	All	All	+0.022	.016	2	view →
ESCA	All	All	−0.077	.031	1	view →
LUSC	Female	All	−0.030	.044	1	view →
KIRC	All	All	+0.026	.046	1	view →
COAD	All	II,III,IV	−0.014	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

GAPDHP34–THCA

Open the THCA breakdown →