GAPDHP33

Across TCGA pan-cancer cohorts, GAPDHP33 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of GAPDHP33’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where GAPDHP33 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GAPDHP33 is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

HNSC, KICH, and BLCA are the cancer types where GAPDHP33 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GAPDHP33 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.068	<.001	10	view →
KICH	Male	All	−0.294	<.001	7	view →
BLCA	Male	III,IV	+0.448	.019	6	view →
CHOL	All	All	+0.496	<.001	5	view →
COAD	All	II,III,IV	+0.097	.007	4	view →
BRCA	All	III,IV	−0.188	<.001	3	view →
STAD	All	All	+0.071	.011	3	view →
LIHC	Male	All	+0.048	.004	3	view →
KIRC	Male	III,IV	+0.156	.015	2	view →
ESCA	Female	All	−0.306	.025	1	view →
READ	All	All	+0.228	.013	1	view →
KIRP	Male	All	−0.200	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

GAPDHP33–HNSC

Open the HNSC breakdown →