GAPDHP27

Across TCGA pan-cancer cohorts, GAPDHP27 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of GAPDHP27’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where GAPDHP27 RNA is repressed in tumor relative to normal tissue. In most cancer types GAPDHP27 is over-expressed in tumor, although a few such as KICH and KIRP show the opposite, repressed pattern.

KICH, LUSC, and HNSC are the cancer types where GAPDHP27 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GAPDHP27 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	−0.081	.005	4	view →
LUSC	All	All	+0.061	.011	3	view →
HNSC	All	All	+0.041	.020	3	view →
KIRP	Female	II,III,IV	−0.181	.023	2	view →
STAD	All	IV	+0.133	.029	2	view →
COAD	All	II,III,IV	+0.087	.013	2	view →
LIHC	All	All	+0.035	.010	2	view →
ESCA	Female	All	−0.316	.022	1	view →
KIRC	All	III,IV	+0.079	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

GAPDHP27–KICH

Open the KICH breakdown →