GAPDH

Across TCGA patient cohorts, GAPDH RNA expression is significantly associated with the protein abundance of many other proteins, with 18,594 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible GAPDH-associated proteins across cancer lineages are NIP7, NOP2, and KDM3A. Each is linked with GAPDH in more than 8 cancer types. Because this analysis shows association rather than direction, both GAPDH-to-partner and partner-to-GAPDH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GAPDH versus NIP7 in PDAC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GAPDH→partner) and Y-score (partner→GAPDH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	NIP7 →	+0.398	+0.728	<.001	<.001	3	9
LUAD	NOP2 →	+0.448	+0.751	<.001	<.001	3	9
CCRCC	KDM3A →	+0.354	+0.611	<.001	<.001	3	9
LUAD	TPI1_S80 →	+0.610	+0.656	<.001	<.001	3	8
LUAD	MCM4 →	+0.685	+0.616	<.001	<.001	3	8
COAD	MCM5 →	+0.618	+0.807	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,594 associations by consensus.

GAPDH vs NIP7 — PDAC

Explore this scatter interactively →