GAPDH

Across TCGA patient cohorts, GAPDH protein abundance is significantly associated with the RNA expression of many other genes, with 18,537 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GAPDH-associated genes across cancer lineages are TPI1, MRPL51, and PPFIA4. Each is linked with GAPDH in more than 6 cancer types. Because this analysis shows association rather than direction, both GAPDH-to-partner and partner-to-GAPDH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GAPDH versus TPI1 in UCEC, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAPDH→partner) and Y-score (partner→GAPDH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TPI1 →	+1.002	+0.218	.005	.001	3	7
OV	MRPL51 →	+0.597	+0.402	<.001	<.001	3	6
CCRCC	PPFIA4 →	+1.121	+0.327	<.001	<.001	3	6
OV	GAPDHP72 →	+1.748	+0.621	<.001	<.001	3	6
OV	GAPDHP63 →	+2.229	+0.605	<.001	<.001	3	6
OV	GAPDHP1 →	+1.909	+0.667	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,537 associations by consensus.

GAPDH vs TPI1 — UCEC

Explore this scatter interactively →