GAPDH

Across TCGA cell cohorts, GAPDH RNA expression is significantly associated with the go_rna of many other GO terms, with 3,733 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible GAPDH-associated GO terms across cancer lineages are Carbohydrate biosynthetic process, Nucleoside diphosphate metabolic process, and Establishment or maintenance of microtubule cytoskeleton polarity. Each is linked with GAPDH in more than 10 cancer types. Because this analysis shows association rather than direction, both GAPDH-to-partner and partner-to-GAPDH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Carbohydrate biosynthetic process grouped by GAPDH-low versus GAPDH-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GAPDH→partner) and Y-score (partner→GAPDH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Carbohydrate biosynthetic process →	+0.106	+0.953	.003	.003	3	11
OVARY	Nucleoside diphosphate metabolic process →	+0.106	+0.747	<.001	.001	3	11
BLOOD_Myeloma	Establishment or maintenance of microtubule cytoskeleton polarity →	+0.233	+1.106	.007	.003	3	10
CNS	Establishment or maintenance of cytoskeleton polarity →	+0.194	+0.949	<.001	<.001	3	10
OVARY	Pyruvate metabolic process →	+0.087	+0.894	.002	<.001	2	11
LIVER	ADP metabolic process →	+0.117	+0.887	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,733 associations by consensus.

Carbohydrate biosynthetic process by GAPDH expression — KIDNEY

Explore this box plot interactively →