GALP

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GALP mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GALP-associated genes across cancer lineages are EGFR_pY1068, eIF4G, and ERK2. Each is linked with GALP in more than 1 cancer types. Because this analysis shows association rather than direction, both GALP-to-partner and partner-to-GALP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALP→partner) and Y-score (partner→GALP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECEGFR_pY1068 →-0.295-3.459.019.00531
UCECeIF4G →+0.356+2.321.022.03531
UCECERK2 →+0.205+3.000.034.03631
UCECMEK1 →+0.388+3.169.034.01931
UCECRictor_pT1135 →-0.122-2.321.017.03531
UCECTFRC →+0.767+2.321.003.03531
Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration