GALNT16

Across TCGA patient cohorts, GALNT16 mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GALNT16-associated genes across cancer lineages are Bim, MSH2, and Caspase-7-cleavedD198. Each is linked with GALNT16 in more than 1 cancer types. Because this analysis shows association rather than direction, both GALNT16-to-partner and partner-to-GALNT16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Bim grouped by GALNT16-low versus GALNT16-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT16→partner) and Y-score (partner→GALNT16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Bim →	-0.270	-2.321	.042	.035	3	2
UCEC	MSH2 →	-0.192	-3.143	.038	.018	3	2
UCEC	Caspase-7-cleavedD198 →	+0.612	+2.019	.010	.017	3	2
SKCM	MSH6 →	+0.404	+3.000	.012	.034	3	1
SKCM	Akt →	+0.329	+2.321	.030	.035	3	1
SKCM	Akt_pS473 →	+0.701	+3.459	.009	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

Bim by GALNT16 expression — SKCM

Explore this box plot interactively →