GALNT12

Across TCGA patient cohorts, GALNT12 mutation is significantly associated with the RNA expression of many other genes, with 2,422 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GALNT12-associated genes across cancer lineages are ERCC6L2, CLN8, and CEP57L1. Each is linked with GALNT12 in more than 1 cancer types. Because this analysis shows association rather than direction, both GALNT12-to-partner and partner-to-GALNT12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERCC6L2 grouped by GALNT12-low versus GALNT12-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT12→partner) and Y-score (partner→GALNT12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERCC6L2 →	+0.376	+2.321	.003	.001	3	2
UCEC	CLN8 →	+0.442	+1.947	<.001	.003	3	2
UCEC	CEP57L1 →	+0.346	+2.849	.008	.001	3	2
UCEC	IQGAP3 →	+0.627	+3.353	.003	.005	3	2
UCEC	RPL23AP82 →	+0.424	+2.332	<.001	<.001	3	2
UCEC	ERCC6L →	+0.556	+1.925	.002	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,422 associations by consensus.

ERCC6L2 by GALNT12 expression — UCEC

Explore this box plot interactively →