GALNT12

Across TCGA pan-cancer cohorts, GALNT12 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of GALNT12’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where GALNT12 RNA is repressed in tumor relative to normal tissue. In most cancer types GALNT12 is over-expressed in tumor, although a few such as COAD and HNSC show the opposite, repressed pattern.

COAD, HNSC, and KICH are the cancer types where GALNT12 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GALNT12 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	All	−1.527	<.001	11	view →
HNSC	Female	All	−1.512	<.001	11	view →
KICH	Male	All	−2.115	<.001	10	view →
KIRP	Male	II,III,IV	+1.219	<.001	9	view →
KIRC	Male	All	+0.630	<.001	8	view →
READ	All	II,III,IV	−1.767	<.001	7	view →
LUSC	Female	II,III,IV	−1.385	<.001	7	view →
BRCA	All	III,IV	−1.190	<.001	6	view →
THCA	Male	II,III,IV	+0.517	.003	6	view →
LIHC	Female	All	+0.702	.004	4	view →
CHOL	Male	All	+2.778	<.001	2	view →
PAAD	All	All	+1.749	.032	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

GALNT12–COAD

Open the COAD breakdown →