GALNT12

Across TCGA patient cohorts, GALNT12 mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GALNT12-associated genes across cancer lineages are EGFR_pY1068, 4E-BP1, and 14-3-3_beta. Each is linked with GALNT12 in more than 1 cancer types. Because this analysis shows association rather than direction, both GALNT12-to-partner and partner-to-GALNT12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1068 grouped by GALNT12-low versus GALNT12-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT12→partner) and Y-score (partner→GALNT12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.209	-2.000	.033	.010	3	2
UCEC	4E-BP1 →	+0.257	+3.199	.015	.009	3	2
UCEC	14-3-3_beta →	-0.088	-2.301	.025	.034	3	1
UCEC	eIF4E →	+0.181	+2.000	.028	.010	3	1
UCEC	ERK2 →	+0.216	+3.459	.004	.005	3	1
UCEC	JNK_pT183_Y185 →	-0.144	-2.000	.030	.030	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

EGFR_pY1068 by GALNT12 expression — UCEC

Explore this box plot interactively →