GALNT12

Across TCGA cell cohorts, GALNT12 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,655 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible GALNT12-associated GO terms across cancer lineages are Negative regulation of actin filament polymerization, Late endosome to lysosome transport, and Positive regulation of protein localization to plasma membrane. Each is linked with GALNT12 in more than 9 cancer types. Because this analysis shows association rather than direction, both GALNT12-to-partner and partner-to-GALNT12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of actin filament polymerization grouped by GALNT12-low versus GALNT12-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT12→partner) and Y-score (partner→GALNT12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of actin filament polymerization →	+0.126	+2.334	.004	<.001	3	10
PANCREAS	Late endosome to lysosome transport →	+0.116	+1.768	<.001	<.001	3	8
OESOPHAGUS	Positive regulation of protein localization to plasma membrane →	+0.092	+1.836	<.001	<.001	3	8
LUNG_NSCLC_LUAD	ERBB3 signaling pathway →	+0.185	+1.609	<.001	<.001	3	8
LUNG_NSCLC_LUAD	ERBB2-ERBB3 signaling pathway →	+0.185	+1.609	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.077	+1.386	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,655 associations by consensus.

Negative regulation of actin filament polymerization by GALNT12 expression — OESOPHAGUS

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