GALNT11

Across TCGA patient cohorts, GALNT11 mutation is significantly associated with the RNA expression of many other genes, with 2,902 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GALNT11-associated genes across cancer lineages are MFSD12, POLR2E, and SGTA. Each is linked with GALNT11 in more than 2 cancer types. Because this analysis shows association rather than direction, both GALNT11-to-partner and partner-to-GALNT11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MFSD12 grouped by GALNT11-low versus GALNT11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT11→partner) and Y-score (partner→GALNT11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MFSD12 →	+0.409	+2.295	.002	<.001	3	3
UCEC	POLR2E →	+0.601	+3.115	<.001	<.001	3	3
UCEC	SGTA →	+0.585	+3.776	<.001	<.001	3	3
UCEC	SLC66A2 →	+0.445	+2.928	<.001	<.001	3	3
CESC	RN7SL248P →	+0.096	+6.000	<.001	<.001	3	3
UCEC	TRAJ47 →	+0.428	+1.953	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,902 associations by consensus.

MFSD12 by GALNT11 expression — UCEC

Explore this box plot interactively →