GALK1

Across TCGA cell cohorts, GALK1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,359 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GALK1-associated GO terms across cancer lineages are Galactose catabolic process via UDP-galactose, Leloir pathway, Carbohydrate catabolic process, and Hexose metabolic process. Each is linked with GALK1 in more than 15 cancer types. Because this analysis shows association rather than direction, both GALK1-to-partner and partner-to-GALK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Galactose catabolic process via UDP-galactose, Leloir pathway grouped by GALK1-low versus GALK1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GALK1→partner) and Y-score (partner→GALK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Galactose catabolic process via UDP-galactose, Leloir pathway →	+0.194	+1.282	.001	<.001	3	16
LUNG_SCLC	Carbohydrate catabolic process →	+0.069	+1.221	.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Hexose metabolic process →	+0.066	+0.810	<.001	<.001	3	12
LUNG_SCLC	Hexose catabolic process →	+0.128	+1.106	.004	<.001	3	12
LUNG_SCLC	Monosaccharide metabolic process →	+0.072	+0.957	.004	.002	3	10
BONE	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.120	+1.075	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,359 associations by consensus.

Galactose catabolic process via UDP-galactose, Leloir pathway by GALK1 expression — OESOPHAGUS

Explore this box plot interactively →