GALK1

Across TCGA pan-cancer cohorts, GALK1 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of GALK1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where GALK1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GALK1 is over-expressed in tumor, although a few such as KICH and CHOL show the opposite, repressed pattern.

COAD, BLCA, and KICH are the cancer types where GALK1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GALK1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	All	+1.815	<.001	11	view →
BLCA	Male	All	+0.913	<.001	11	view →
KICH	Female	All	−1.783	<.001	8	view →
THCA	All	II,III,IV	+0.391	<.001	7	view →
BRCA	All	III,IV	+0.694	<.001	6	view →
UCEC	All	All	+0.495	.004	6	view →
STAD	All	II,III,IV	+0.587	.002	5	view →
LIHC	Male	All	+1.087	<.001	3	view →
CHOL	All	All	−0.974	<.001	3	view →
KIRC	Male	III,IV	+0.438	.010	3	view →
READ	Female	All	+1.315	<.001	2	view →
LUSC	Male	II,III,IV	+0.406	.044	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

GALK1–COAD

Open the COAD breakdown →