GALC

Across TCGA patient cohorts, GALC RNA expression is significantly associated with the protein abundance of many other proteins, with 14,520 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GALC-associated proteins across cancer lineages are DDX21, EHD2, and PACS2. Each is linked with GALC in more than 6 cancer types. Because this analysis shows association rather than direction, both GALC-to-partner and partner-to-GALC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GALC versus DDX21 in BRCA, with a Pearson correlation of -0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GALC→partner) and Y-score (partner→GALC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DDX21 →	-0.589	-0.671	<.001	<.001	3	6
LSCC	EHD2 →	+0.555	+0.643	<.001	<.001	3	6
GBM	PACS2 →	+0.252	+0.315	.001	.008	2	7
BRCA	PDCD11 →	-0.391	-0.715	<.001	<.001	3	6
BRCA	GMPR2 →	+0.460	+0.805	<.001	<.001	3	6
BRCA	MYO1C →	+0.449	+0.703	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,520 associations by consensus.

GALC vs DDX21 — BRCA

Explore this scatter interactively →