GALC

Across TCGA patient cohorts, GALC protein abundance is significantly associated with the RNA expression of many other genes, with 4,299 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GALC-associated genes across cancer lineages are SPATA7, SHLD2P2, and ZNF706. Each is linked with GALC in more than 3 cancer types. Because this analysis shows association rather than direction, both GALC-to-partner and partner-to-GALC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GALC versus SPATA7 in UCEC, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALC→partner) and Y-score (partner→GALC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SPATA7 →	+0.348	+0.423	.008	.003	3	4
UCEC	SHLD2P2 →	+0.754	+0.593	<.001	.001	3	4
LSCC	ZNF706 →	-0.466	-0.327	.001	.002	3	3
OV	GART →	-0.498	-0.621	.001	<.001	3	3
CCRCC	DESI1 →	-0.355	-0.387	<.001	.006	3	2
BRCA	PFDN4 →	-0.615	-0.491	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,299 associations by consensus.

GALC vs SPATA7 — UCEC

Explore this scatter interactively →