GALC

Across TCGA cell cohorts, GALC RNA expression is significantly associated with the go_rna of many other GO terms, with 4,211 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GALC-associated GO terms across cancer lineages are Galactolipid catabolic process, Galactosylceramide metabolic process, and Galactolipid metabolic process. Each is linked with GALC in more than 19 cancer types. Because this analysis shows association rather than direction, both GALC-to-partner and partner-to-GALC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Galactolipid catabolic process grouped by GALC-low versus GALC-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GALC→partner) and Y-score (partner→GALC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Galactolipid catabolic process →	+2.148	+3.187	<.001	<.001	3	20
BLOOD_Leukemia	Galactosylceramide metabolic process →	+1.698	+2.310	<.001	<.001	3	17
BLOOD_Leukemia	Galactolipid metabolic process →	+1.753	+2.310	<.001	<.001	3	16
BLOOD_Myeloma	Glycosylceramide catabolic process →	-0.280	-2.467	<.001	<.001	3	11
URINARY_TRACT	Golgi vesicle transport →	+0.061	+2.360	<.001	.002	3	11
LARGE_INTESTINE	Protein localization to vacuole →	+0.049	+1.615	.002	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,211 associations by consensus.

Galactolipid catabolic process by GALC expression — OESOPHAGUS

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