GAL3ST2

Across TCGA patient cohorts, GAL3ST2 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible GAL3ST2-associated genes across cancer lineages are Megakaryocytes, Smooth muscle, and CD8+ naive T-cells. Each is linked with GAL3ST2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GAL3ST2-to-partner and partner-to-GAL3ST2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Megakaryocytes grouped by GAL3ST2-low versus GAL3ST2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAL3ST2→partner) and Y-score (partner→GAL3ST2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Megakaryocytes →	+0.045	+3.082	.001	.017	3	1
SKCM	Smooth muscle →	-0.170	-2.993	.006	.037	1	1
UCEC	CD8+ naive T-cells →	+0.056	+2.850	<.001	.035	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Megakaryocytes by GAL3ST2 expression — SKCM

Explore this box plot interactively →