GAL3ST1

Across TCGA pan-cancer cohorts, GAL3ST1 mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated GAL3ST1 data layer compared with 28 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher GAL3ST1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated GAL3ST1 expression acts as an unfavorable survival marker.

CCRCC are the cancer types where GAL3ST1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	III,IV	0.371	0.750	.003	12	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

GAL3ST1–CCRCC (DFS)

Open the CCRCC breakdown →