GAL3ST1

Across TCGA patient cohorts, GAL3ST1 mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GAL3ST1-associated genes across cancer lineages are eIF4E, MEK1, and PI3K-p85. Each is linked with GAL3ST1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GAL3ST1-to-partner and partner-to-GAL3ST1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by GAL3ST1-low versus GAL3ST1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAL3ST1→partner) and Y-score (partner→GAL3ST1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.183	+1.765	.020	.014	3	2
UCEC	MEK1 →	+0.352	+2.000	.010	.030	3	2
UCEC	PI3K-p85 →	+0.174	+2.459	.027	.018	3	2
UCEC	Rictor_pT1135 →	-0.102	-2.115	.007	.017	3	2
UCEC	TFRC →	+0.396	+3.169	.046	.018	3	2
UCEC	Tuberin →	+0.199	+1.594	.049	.042	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

eIF4E by GAL3ST1 expression — UCEC

Explore this box plot interactively →