GAL3ST1

Across TCGA cell cohorts, GAL3ST1 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GAL3ST1-associated genes across cancer lineages are PYGO1, MYOZ1, and TAFA1. Each is linked with GAL3ST1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GAL3ST1-to-partner and partner-to-GAL3ST1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PYGO1 grouped by GAL3ST1-low versus GAL3ST1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAL3ST1→partner) and Y-score (partner→GAL3ST1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PYGO1 →	+0.808	+3.539	.006	.004	3	1
LARGE_INTESTINE	MYOZ1 →	+0.251	+3.722	.004	.002	3	1
LARGE_INTESTINE	TAFA1 →	+0.208	+2.688	.003	.008	3	1
LARGE_INTESTINE	FAM205A →	+0.023	+3.029	<.001	.003	3	1
BLOOD_Leukemia	SYCN →	+0.037	+4.539	<.001	.007	3	1
BLOOD_Leukemia	TEX43 →	+0.105	+4.969	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

PYGO1 by GAL3ST1 expression — LARGE_INTESTINE

Explore this box plot interactively →