GAK

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GAK RNA expression is significantly associated with the go_rna of many other GO terms, with 7,155 significant associations in total. OV shows the largest number of these associations.

The most reproducible GAK-associated GO terms across cancer lineages are Obsolete regulation of histone methylation, Endocytic recycling, and Autophagosome maturation. Each is linked with GAK in more than 25 cancer types. Because this analysis shows association rather than direction, both GAK-to-partner and partner-to-GAK results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GAK→partner) and Y-score (partner→GAK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SCLCObsolete regulation of histone methylation →+0.150+0.695<.001<.001326
SCLCEndocytic recycling →+0.086+0.840<.001<.001326
SCLCAutophagosome maturation →+0.078+0.716<.001<.001326
SCLCCytosolic transport →+0.082+1.103<.001<.001325
SCLCObsolete histone methylation →+0.130+0.825<.001<.001325
SCLCPositive regulation of intracellular steroid hormone receptor signaling pathway →+0.193+0.763<.001<.001325
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,155 associations by consensus.

Exploration