GAK

Across TCGA patient cohorts, GAK protein abundance is significantly associated with the RNA expression of many other genes, with 15,035 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GAK-associated genes across cancer lineages are RBM47, TADA2B, and SMIM14. Each is linked with GAK in more than 7 cancer types. Because this analysis shows association rather than direction, both GAK-to-partner and partner-to-GAK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GAK versus RBM47 in OV, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAK→partner) and Y-score (partner→GAK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RBM47 →	+1.056	+0.453	<.001	<.001	3	8
BRCA	TADA2B →	+0.580	+0.198	<.001	<.001	3	8
BRCA	SMIM14 →	+1.005	+0.232	<.001	<.001	3	6
LSCC	GPR161 →	-0.830	-0.210	<.001	<.001	3	6
COAD	LDLRAD3 →	-0.914	-0.251	<.001	<.001	3	6
UCEC	PLAAT4 →	+1.906	+0.192	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,035 associations by consensus.

GAK vs RBM47 — OV

Explore this scatter interactively →